2020 | 研究・実績

2020年

  • Wada K, Kumagai G, Kudo H, Asari T, Ota S, Kamei K, Koyama K, Nakaji S, Ishibashi Y. Prevalence of cervical canal stenosis in farmers: Epidemiological study based on radiographic parameter of spinal cord injury patients. J Orthop Sci. 2020 Mar;25(2):206-212PUBMED >
  • Sasaki E, Ota S, Chiba D, Kimura Y, Sasaki S, Yamamoto Y, Tsuda E, Nakaji S, Ishibashi Y. Early knee osteoarthritis prevalence is highest among middle-aged adult females with obesity based on new set of diagnostic criteria from a large sample cohort study in the Japanese general population. Knee Surg Sports Traumatol Arthrosc. 2020 Mar;28(3):984-994.PUBMED >
  • Ozato N, Saito S, Yamaguchi T, Katashima M, Tokuda I, Sawada K, Katsuragi Y, Kakuta M, Imoto S, Ihara K, Nakaji S. Association between breath methane concentration and visceral fat area: a population-based cross-sectional study. J Breath Res. 2020 Feb 25;14(2):026008.PUBMED >
  • Nomura A, Matsubara A, Goto S, Takahata J, Sawada K, Ihara K, Nakaji S. Relationship between gut microbiota composition and sensitization to inhaled allergens.Allergol Int. 2020 Jul;69(3):437-442.PUBMED >
  • Yamaguchi T, Ozato N Katashima M, Sawada K, Katsuragi Y, Ihara K, Nakaji S. A Novel Method to Visualize the Dietary Macronutrient Composition of Smaller Visceral Fat Accumulation. Front Nutr. 2020 Jan 24;6:194.PUBMED >
  • Okamoto T, Hatakeyama S, Imai A, Yamamoto H, Yoneyama T, Mori K, Yoneyama T, Hashimoto Y, Nakaji S, Ohyama C. The association between gut microbiome and erectile dysfunction: a community-based cross-sectional study in Japan. Int Urol Nephrol. 2020 Int Urol Nephrol. 2020 Aug;52(8):1421-1428.PUBMED >
  • Murabayashi M, Daimon M, Murakami H, Fujita T, Sato E, Tanabe J, Matsuhashi Y, Takayasu S, Yanagimachi M, Terui K, Kageyama K, Tokuda I, Sawada K, Ihara K. Association between higher urinary normetanephrine and insulin resistance in a Japanese population. PLoS One. 2020 Feb 13;15(2):e0228787.PUBMED >
  • Iino C, Shimoyama T, Chinda D, Sakuraba H, Fukuda S, Nakaji S. Influence of Helicobacter pylori Infection and Atrophic Gastritis on the Gut Microbiota in a Japanese Population. Digestion. 2020;101(4):422-432.PUBMED >
  • Sato N, Kakuta M, Hasegawa T, Yamaguchi R, Uchino E, Kobayashi W, Sawada K, Tamura Y, Tokuda I, Murashita K, Nakaji S, Imoto S, Yanagita M, Okuno Y. Metagenomic analysis of bacterial species in tongue microbiome of current and never smokers. NPJ Biofilms Microbiomes. 2020;6(1):11.PUBMED >
  • Sato N, Kakuta M, Uchino E, Hasegawa T, Kojima R, Kobayashi W, Sawada K, Tamura Y, Tokuda I, Imoto S, Nakaji S, Murashita K, Yanagita M, Okuno Y. The relationship between cigarette smoking and the tongue microbiome in an East Asian population. J Oral Microbiol. 2020;Mar 25;12(1):1742527.PUBMED >
  • Sato N, Kakuta M, Hasegawa T, Yamaguchi R, Uchino E, Murashita K, Nakaji S, Imoto S, Yanagita M, Okuno Y. Metagenomic profiling of gut microbiome in early chronic kidney disease. Nephrol Dial Transplant. 2020 Sep 1:gfaa172.PUBMED >
  • Ichinohe M, Wada K, Kumagai G, Tanaka S, Asari T, Takeda O, Ota S, Koyama K, Ihara K, Nakaji S, Ishibashi Y. Prevalence and associated factors of radiographic vertebral fractures in men: Rural population cross-sectional observation study in Japan. J Orthop Sci. 2020:Sep 5;S0949-2658(20)30207-4.PUBMED >
  • Kawabata R, Soma Y, Kudo Y, Yokoyama J, Shimizu H, Akaike A, Suzuki D, Katsuragi Y, Totsuka M, Nakaji S. Relationships between body composition and pulmonary function in a community-dwelling population in Japan. PLoS One.2020;Nov 17;15(11):e0242308.PUBMED >
  • Soma O, Hatakeyama S, Imai A, Matsumoto T, Hamano I, Fujita N, Iwamura H, Okamoto T, Yamamoto H, Tobisawa Y, Yoneyama T, Yoneyama T, Hashimoto Y, Nakaji S, Ohyama C. Relationship between frailty and lower urinary tract symptoms among community-dwelling adults. Low Urin Tract Symptoms. 2020 May;12(2):128-136.PUBMED >
  • Osonoi S, Mizukami H, Itabashi C, Wada K, Kudoh K, Igawa A, Ogasawara S, Ishibashi Y, Daimon M, Yagihashi S, Nakaji S. Increased Oxidative Stress Underlies Abnormal Pain Threshold in a Normoglycemic Japanese Population. Int J Mol Sci. 2020 Nov 5;21(21):8306.PUBMED >
  • Okita K, Hatakeyama S, Imai A, Tanaka T, Hamano I, Okamoto T, Tobisawa Y, Yoneyama T, Yamamoto H, Yoneyama T, Hashimoto Y, Nakaji S, Suzuki T, Ohyama C. STone Episode Prediction: Development and validation of the prediction nomogram for urolithiasis. Int J Urol. 2020 Apr;27(4):344-349.PUBMED >
  • Wai KM, Sawada K, Kumagai M, Itai K, Tokuda I, Murashita K, Nakaji S, Ihara K. Relationship between Selected Trace Elements and Hematological Parameters among Japanese Community Dwellers. Nutrients. 2020 May 30;12(6):1615.PUBMED >
  • Kudoh K, Mizukami H, Itabashi C, Fuke N, Osonoi S, Takeuchi Y, Wada K, Igawa A, Ogasawara S, Ishibashi Y, Hakamada K, Yagihashi S, Nakaji S. Lipopolysaccharide-binding protein is a distinctive biomarker of abnormal pain threshold in the general Japanese population. BMJ Open Diabetes Res Care. 2020 Oct;8(1):e001739.PUBMED >
  • Hasegawa T, Iino C, Endo T, Mikami K, Kimura M, Sawada N, Nakaji S, Fukuda S. Changed Amino Acids in NAFLD and Liver Fibrosis: A Large Cross-Sectional Study without Influence of Insulin Resistance. Nutrients. 2020 May 17;12(5):1450.PUBMED >
  • Shimizu S, Mimura J, Hasegawa T, Shimizu E, Imoto S, Tsushima M, Kasai S, Yamazaki H, Ushida Y, Suganuma H, Tomita H, Yamamoto M, Nakaji S, Itoh K. Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging. PLoS One. 2020 Aug 11;15(8):e0236834.PUBMED >
  • Mikami K, Endo T, Sawada N, Igarashi G, Kimura M, Hasegawa T, Iino C, Sawada K, Nakaji S, Ishibashi Y, Matsuzaka M, Fukuda S. Association of Bone Metabolism with Fatty Liver Disease in the Elderly in Japan: A Community-based Study. Intern Med. 2020 May 15;59(10):1247-1256.PUBMED >
  • Suzuki N, Sawada K, Takahashi I, Matsuda M, Fukui S, Tokuyasu H, Shimizu H, Yokoyama J, Akaike A, Nakaji S. Association between Polyunsaturated Fatty Acid and Reactive Oxygen Species Production of Neutrophils in the General Population.
    Nutrients. 2020 Oct 22;12(11):3222. PUBMED >
  • Matsumoto M, Waki N, Suganuma H, Takahashi I, Kurauchi S, Sawada K, Tokuda I, Misawa M, Ando M, Itoh K, Ihara K, Nakaji S. Association between Biomarkers of Cardiovascular Diseases and the Blood Concentration of Carotenoids among the General Population without Apparent Illness. Nutrients. 2020 Jul 31;12(8):2310.PUBMED >
  • Chiba D, Sasaki E, Ota S, Maeda S, Sugiyama D, Nakaji S, Ishibashi Y. US detection of medial meniscus extrusion can predict the risk of developing radiographic knee osteoarthritis: a 5-year cohort study. Eur Radiol. 2020 Jul;30(7):3996-4004.PUBMED >
  • Chiba D, Ota S, Sasaki E, Tsuda E, Nakaji S, Ishibashi Y. Knee effusion evaluated by ultrasonography warns knee osteoarthritis patients to develop their muscle atrophy: a three-year cohort study. Sci Rep. 2020 May 21;10(1):8444.PUBMED >
  • Kimura M, Mikami K, Endo T, Matsuzaka M, Sawada N, Igarashi G, Iino C, Hasegawa T, Sawada K, Ando M, Tokuda I, Suganuma H, Matsumoto M, Nakaji S, Fukuda S. Association between serum β-carotene-to-retinol ratio and severity of hepatic steatosis in non-alcoholic fatty liver disease in Japan: A cross-sectional study. Nutrition. 2020 Nov-Dec;79-80:110984.PUBMED >
  • Matsumoto M, Suganuma H, Shimizu S, Hayashi H, Sawada K, Tokuda I, Ihara K, Nakaji S. Skin Carotenoid Level as an Alternative Marker of Serum Total Carotenoid Concentration and Vegetable Intake Correlates with Biomarkers of Circulatory Diseases and Metabolic Syndrome. Nutrients. 2020 Jun 19;12(6):1825.PUBMED >
  • Ishibashi K, Sasaki E, Ota S, Chiba D, Yamamoto Y, Tsuda E, Yoshikuni S, Ihara K, Ishibashi Y. Detection of synovitis in early knee osteoarthritis by MRI and serum biomarkers in Japanese general population. Sci Rep. 2020 Jul 23;10(1):12310.PUBMED >
  • Maeda Y, Sasaki A, Kasai S, Goto S, Nishio SY, Sawada K, Tokuda I, Itoh K, Usami SI, Matsubara A. Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan. Hum Genome Var. 2020 Sep 18;7:27.PUBMED >
  • Makoto Daimon, Tomoyuki Fujita, Masaya Murabayashi, Satoru Mizushiri, Hiroshi Murakami, Yuki Nishiya, Jutaro Tanabe, Yuki Matsuhashi, Miyuki Yanagimachi, Itoyo Tokuda, Kaori Sawada, Kazushige Ihara. Exacerbation of Hyperparathyroidism, Secondary to a Reduction in Kidney Function, in Individuals With Vitamin D Deficiency. Front Med (Lausanne). 2020 Jun 5;7:221.PUBMED >
  • Kyota Ishibashi, Eiji Sasaki, Seiya Ota, Daisuke Chiba, Yuji Yamamoto, Eiichi Tsuda, Sugimura Yoshikuni, Kazushige Ihara, and Yasuyuki Ishibashi. Detection of synovitis in early knee osteoarthritis by MRI and serum biomarkers in Japanese general population. Sci Rep. 2020;10:12310.PUBMED >
  • Tomoyuki Fujita, Makoto Daimon, Satoru Mizushiri, Yuki Nishiya, Hiroshi Murakami, Jutaro Tanabe, Yuki Matsuhashi, Miyuki Yanagimachi, Itoyo Tokuda, Kaori Sawada, and Kazushige Ihara. FIB-4 index is a marker for a subsequent decrease in insulin secretion in a non-diabetic Japanese population. Sci Rep. 2020;10:15814.PUBMED >
  • Yuki Nishiya, Makoto Daimon, Satoru Mizushiri, Hiroshi Murakami, Jutaro Tanabe, Yuki Matsuhashi, Miyuki Yanagimachi, Itoyo Tokuda, Kaori Sawada, and Kazushige Ihara. Nutrient consumption-dependent association of a glucagon-like peptide-1 receptor gene polymorphism with insulin secretion. Sci Rep. 2020;10:16382.PUBMED >
  • Teppei Okamoto, Shingo Hatakeyama, Masataka Ando, Jung Songee, Atsushi Imai, Itsuto Hamano, Naoki Fujita, Akiko Okamoto, Hayato Yamamoto, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Chikara Ohyama. The impact of microalbuminuria on overactive bladders: Results from a community-based four-year longitudinal study in Japan. Neurourol Urodyn. 2020. Jun;39(5):1567-1575.PUBMED >
弘前大学健康未来イノベーション研究機構